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Ginger (Zingiber officinale)Digestive

Ginger (Zingiber officinale)

Overview

Ginger (Zingiber officinale) is a perennial plant reaching about 2 ft (60 cm), with lance-shaped leaves and white or yellowish flower spikes. Its rhizome (underground stem) is pungent, aromatic, and widely esteemed as both a culinary spice and a potent herbal medicine. Ginger’s warming, anti-inflammatory qualities can ease many digestive and circulatory problems, as well as reduce pain from arthritis and menstrual cramps.

Traditional uses & properties

Antiemetic & Digestive Stimulant: Relieves nausea, motion sickness, gas, bloating, and aids nutrient absorption. Anti-Inflammatory & Analgesic: Research shows it can reduce pain in arthritis, menstrual cramps, and may help with migraines. Antiviral & Respiratory Support: Valuable for colds, flu, bronchial infections; encourages sweating and helps lower fevers. Circulatory Stimulant & Warming: Aids blood flow to extremities, easing chilblains and cold hands/feet.

Preparations & dosage

Indigestion

Make a tincture and take 30 drops with water twice a day.

Safety & precautions

Ulcers & High Doses: Not advised in medicinal amounts for peptic ulcers; do not take essential oil internally except under professional supervision. Pregnancy & Blood-Thinners: While ginger is commonly used for morning sickness, doses above 2 g dried (4 g fresh) per day should be taken under supervision if pregnant or on anticoagulant medication. Gastric Irritation: May cause mild stomach upset; taking it with food can help.

Drug & food interactions

There are isolated cases of ginger increasing the response to anticoagulant treatment with warfarin and related drugs, but a controlled study did not confirm an interaction. A small study showed antiplatelet effects for ginger that were synergistic with those of nifedipine, but any effect needs confirming.

Food

No interactions found. Ginger is extensively used as a food ingredient.

Nifedipine

A small study found that antiplatelet effects for ginger were synergistic with those of nifedipine, but any effect needs confirmation.

Anticoagulants

Evidence from pharmacological studies suggests that ginger does not increase the anticoagulant effect of warfarin, nor does it alter coagulation or platelet aggregation on its own. However, two case reports describe markedly raised INRs with phenprocoumon and warfarin, which were associated with eating dried ginger and drinking ginger tea. A prospective, longitudinal study also reports an increased risk of self-reported bleeding events in patients taking warfarin and ginger. In a randomised, crossover study in 12 healthy subjects, 3 ginger capsules taken three times daily for 2 weeks did not affect either the pharmacokinetics or pharmacodynamics (INR) of a single 25-mg dose of warfarin taken on day 7. The brand of ginger used was Blackmores Travel Calm Ginger, each capsule containing an extract equivalent to 400 mg of ginger rhizome powder. Moreover, ginger alone did not affect the INR or platelet aggregation.1 However, a case report describes a rise in INR to greater than 10, with epistaxis, in a woman stabilised on phenprocoumon several weeks after she started to eat ginger regularly in the form of pieces of dried ginger and tea from ginger powder. She was eventually restabilised on the original dose of phenprocoumon, and was advised to stop taking ginger.2 Another very similar case has been described in a woman taking warfarin.3 Moreover, in a prospective, longitudinal study of patients taking warfarin and a herbal product or dietary supplement, there was a statistically significant increased risk of self-reported bleeding events in patients taking warfarin and ginger (7 bleeds in 25 weeks, none of which was major: odds ratio 3.2).4 No elevated INRs were reported for the combination. Note that the number of patients taking ginger was not reported, except to say it was less than 5% of 171 – so it was less than 8 patients. Also, the ginger products used were not mentioned and some patients were taking more than one potentially interacting supplement.

Herbal medicines

No interactions found.

Habitat

Native to Asia, ginger is cultivated throughout the tropics, thriving in fertile soil with ample rainfall. It is grown from rootstock divisions. The rhizomes are dug up around 10 months after planting, then washed, dried, and sometimes peeled or boiled.

Traditionally used for

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