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Hawthorn (Crataegus oxyacantha)Circulatory

Hawthorn (Crataegus oxyacantha)

Overview

Hawthorn (Crataegus spp.) is a deciduous, thorny tree reaching up to about 26 ft (8 m), adorned with small lobed leaves, clusters of white blossoms, and bright red berries. Renowned as a cardiac tonic, hawthorn is often called “food for the heart,” enhancing the heart’s strength, improving blood flow to heart muscle, and helping normalize blood pressure. It also reduces stress and assists digestion when used regularly.

Traditional uses & properties

Cardiac & Circulatory Tonic: Strengthens heart muscle, dilates peripheral blood vessels, reduces strain, helps with angina, mild congestive heart failure, and irregular heartbeats. Blood Pressure Normalizer: Can lower high blood pressure but also support normal pressure when low. Antioxidant & Stress-Reducing: Beneficial flavonoids help protect blood vessels from deterioration; also believed to ease nervous tension. Digestive Support: Helps calm upset digestion, particularly stress-related.

Preparations & dosage

High Blood Pressure

Decoction, tincture, and infusion of flower tops can help to restore blood pressure to normal levels.

Safety & precautions

Interactions: Can interact with prescription medications for heart and blood pressure; seek professional advice if already on such drugs. General Safety: Considered safe for long-term use in moderate amounts.

Drug & food interactions

The safety of hawthorn extracts was investigated in a comprehensive systematic review,1 which included data up to January 2005 from the WHO, relevant medical journals and conference proceedings. The investigators found that 166 adverse events were reported in 5577 patients from 24 clinical studies, and 18 cases of adverse events were reported via the WHO spontaneous reporting scheme. None of these involved drug interactions. In the clinical studies assessed, the daily dose and duration of treatment with hawthorn preparations ranged from 160 to 1800 mg and from 3 to 24 weeks, and the extracts most used contained leaves and flowers and were WS 1442 (standardised to 18.75% oligomeric procyanidins) and LI 132 (standardised to 2.25% flavonoids). Other studies do not appear to have identified any clinically significant drug interactions.

Food

No interactions found.

Antidiabetics

Hawthorn does not appear to affect the glycaemic control in patients taking conventional antidiabetic drugs. In a randomised study, 80 patients with type 2 diabetes taking antidiabetics (including metformin, gliclazide and/or low-dose insulin) with or without antihypertensives were given hawthorn extract 600 mg twice daily, or placebo, for 16 weeks. There was no difference between the two groups in measures of glycaemic control (fasting glucose, glycosylated haemoglobin and fructosamine) at 16 weeks. The hawthorn extract used in this study, LI 132, contained dried flowering tops and was standardised to 2.2% flavonoids.

Antihypertensives

Limited evidence suggests that there may be additive blood pressure-lowering effects if hawthorn is taken with conventional antihypertensives, but the effects are small. In a randomised study, 80 patients with type 2 diabetes, of whom 71% were taking antihypertensives (including ACE inhibitors, calcium-channel blockers, beta blockers and/or diuretics), were given hawthorn extract 600 mg twice daily or placebo for 16 weeks. The group given hawthorn extract (39 of 40 patients assessed) had a small additional 2.6mmHg reduction in diastolic blood pressure compared with no change in the placebo group. The 3.6mmHg decline in systolic blood pressure in the hawthorn group was not statistically significant. The hawthorn extract used in this study, LI 132, contained dried flowering tops and was standardised to 2.2% flavonoids.

Herbal medicines

No interactions found.

Digoxin

Hawthorn does not appear to affect digoxin levels. In a randomised, crossover study, 8 healthy subjects were given hawthorn extract 450 mg twice daily with digoxin 250 micrograms daily for 21 days, or digoxin 250 micrograms alone daily for 10 days. While digoxin levels tended to be lower when hawthorn was given (the biggest difference being a 23% reduction in the trough level), these reductions were not statistically significant. There was no change in ECG effects or heart rate, and the combination was well tolerated. The hawthorn extract used in this study, WS 1442, contained an extract of leaves with flowers standardised to 84.3 mg of oligomeric procyanidines.

Habitat

Widely found along roadsides and in hedgerows throughout the British Isles, Europe, and temperate regions of the northern hemisphere, hawthorn can be grown from seed (though slow to germinate) or from cuttings. The flowering tops are harvested in late spring, and berries in late summer to early autumn.

Traditionally used for

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