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Boneset (Eupatorium perfoliatum)General

Boneset (Eupatorium perfoliatum)

Overview

Boneset (Eupatorium perfoliatum) is a bitter-tasting, upright perennial that can reach about 5 ft (1.5 m). It has lance-shaped leaves and clusters of small white or sometimes purple florets. Renowned in traditional American herbal medicine for colds, fevers, and influenza—especially when body aches are severe—it is believed to stimulate white blood cell activity and encourage sweating, thereby reducing fever and supporting the immune response.

Traditional uses & properties

Bitter & Diaphoretic: Encourages perspiration, helping to reduce fevers and ease viral infections such as colds and flu. Immunostimulant: Thought to enhance white blood cell activity, aiding the body in fighting infections. Mild Laxative & Tonic (cold infusion): Supports digestion, helps with bloating, and can lessen vomiting when combined with other carminatives such as mint. Antiprotozoal History: Historically employed against malaria and dengue fever, indicating notable antimicrobial potential.

Preparations & dosage

TINCTURE

Fresh leaf and flowers (1:2, 95% alcohol); dried leaf and flowers (1:5, 35% alcohol); 1–4 ml (0.2–0.8 tsp.) 3 times daily

STANDARD INFUSION

4–8 ounces, hot, 3–5 times daily

GLYCERITE

Dried leaf and flowers (1:6); 3–5 ml (0.6–1 tsp.) 3–4 times daily

Safety & precautions

Pregnancy: Use cautiously during pregnancy. Long-Term Use: Not recommended for prolonged usage. Fresh plant material, large amounts, or chronic intake can cause nausea, diarrhea, and possible liver stress, as boneset contains pyrrolizidine alkaloids (similarly to comfrey). Emetic & Laxative Effects: When taken hot, boneset infusion can promote sweating and may cause vomiting; when taken cold, it acts as a bitter tonic and mild laxative.

Habitat

Native to eastern North America, boneset thrives in marshy areas, meadows, and wetlands. It is collected when in flower during the summer, with the aerial parts (leaves and flowering tops) most commonly used in herbal preparations.

Traditionally used for

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